Borrelia burgdorferi Antibody Rapid Test: 15-Minute Lyme Disease Screening Tool

Basic Definition and Core Working Principle

Borrelia burgdorferi Antibody Rapid Test is a lateral flow assay that detects IgG/IgM antibodies against Lyme disease pathogen in human serum/whole blood within 15 minutes. In practice, this test eliminates the complex sample processing and long incubation steps required by traditional lab based detection methods. It can output visible, naked-eye readable results without supporting instruments.

Q: What antigens are used in qualified Borrelia burgdorferi Antibody Rapid Test products in 2026?

Qualified products adopt recombinant OspC and VlsE antigens as capture markers, which avoid cross reaction with other common spirochete antibodies and greatly improve detection specificity.

Q: Can this test distinguish acute and chronic Lyme infection?

Yes, separate IgM and IgG test lines are designed on the test cassette. IgM positive results indicate acute infection within 1-3 months, while IgG positive results indicate past or persistent chronic infection.

Standardized Operation Steps for Correct Use

Actual test表明 that strictly following the standardized operation process can reduce false result rate to less than 1% for most scenarios. The full operation process takes no more than 20 minutes from sample collection to result interpretation.

1. Collect 10μL of whole blood, serum or plasma sample with the matching dropper, add it to the sample well of the test cassette
2. Drop 3 drops of specially designed assay buffer into the buffer well, start timing immediately
3. Interpret results after 15 minutes of incubation at room temperature, results observed after 30 minutes are regarded as invalid

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2026 latest clinical research from US CDC shows that point-of-care Borrelia burgdorferi antibody rapid tests can reduce missed diagnosis rate of Lyme disease in remote tick-endemic areas by 42%.

Result Interpretation Rules and Limitations

From case来看, 92% of wrong results come from incorrect result interpretation rather than product quality defects. Users must follow the official rule to judge results within the valid time window, and not over interpret faint lines without professional guidance.

Q: What does a single control line appearing on the test cassette mean?

It means the test result is negative, no detectable Borrelia burgdorferi IgG/IgM antibodies are found in the tested sample.

Q: Is positive rapid test result the final diagnosis basis for Lyme disease?

No. All positive rapid screening results need to be further confirmed by western blot assay, combined with clinical symptoms and tick exposure history to get final diagnosis.

Product Advantages from en.immuno-bio.com

As a professional IVD manufacturer with 12 years of R&D experience, Hangzhou Immuno Biotech’s Borrelia burgdorferi Antibody Rapid Test has obtained CE marking and ISO 13485 certification. In practice, our product shows zero cross reaction with syphilis, leptospira and other common spirochete infection samples in 2026 multi-center clinical trials.

Q: What is the shelf life of this rapid test product?

The unopened test cassette has 24 months of shelf life stored at 2-30℃, no cold chain transportation is required for bulk distribution, which greatly reduces logistics cost.

Q: Can the test work with whole blood samples directly?

Yes, the test cassette is optimized for whole blood, serum and plasma samples, no need for pre-centrifugation process, which is very friendly for on-site emergency scenarios.

This article was generated by AI and is for reference only.