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A new mechanism of remote improvement of depression and anxiety like behavior by peripheral mesenchymal stem cells
Major depressive disorder (MDD) is a serious mental illness that seriously affects the lives of patients. At present, the classic drug selective serotonin reuptake inhibitor takes several weeks to take effect, and more than 30% of patients are not sensitive to the drug...
2024-01-22
Large-scale generation of high-purity midbrain dopaminergic progenitor cells from human embryonic stem cells
Recently, researchers at Yonsei University School of Medicine from clinical-grade human embryonic stem cells (hESC) large-scale generation of high-purity midbrain dopaminergic (mDA) progenitor cells, and in vitro and in vivo verification...
2023-12-29
Protein VGLL3 found responsible for increased organ fibrosis
Fibrosis (fibrosis) is the body's response to organ or tissue damage repair response, although fibrosis can quickly compensate for tissue damage, protect the integrity of tissues and organs, but due to the proliferation of fibrous tissue...
Consensus Release Event Medical Institutions Exempt from Ethical Review Implementation Expert Consensus
On February 18, 2023, the National Health Commission, the Ministry of Education, the Ministry of Science and Technology, and the State Administration of Traditional Chinese Medicine jointly issued the "Measures for Ethical Review of Life Sciences and Medical Research Involving People"...
Key Points and Judgment Principles of Supervision and Inspection of Drug Clinical Trial Institutions
On November 3, the website of the Verification Center of the State Food and Drug Administration issued a notice on the key points and judgment principles of supervision and inspection of drug clinical trial institutions (for trial implementation). the full text is as follows...
CMC Series (X): Genotoxic Impurities in Drug Impurity Research Strategies
With regard to impurities, different from the active ingredients of the material we will be referred to as impurities, these ingredients are usually ineffective, with the active ingredients used for purposes unrelated or there are other toxic and side effects of the material...